Probably the original author of this thread will never see this, but the Theatre major in me demands this have further explanation...
It's not the fact that she committed suicide that makes the comic make sense. Here's the relevant parts of the plot of Oedipus Rex... I guess SPOILERS for those who actually haven't seen/read what many consider the pinnacle of ancient drama (not my opinion, but Aristotle freaking loved it).
Oedipus was king of Thebes. He came to be King because he ran away from his home kingdom, due to a prophecy that he would sleep with his mother and kill his father. On his journey running away from home, he came across a man who he got into a fight with and killed. When he reached Thebes, they were being terrorized by the Sphinx; Oedipus answered the Sphinx's riddle, which made it go away. The townspeople rejoiced, and proclaimed Oedipus their king - after all, THEIR king had been killed recently by bandits. He married Jocasta, the former king's wife, and all was well.
Except for when pestilence hit the land. Why? Because of the horrendous sins of one of Thebes townsfolk. Oedipus seeks out the sinner, and in the process finds out two facts that screw him over big time. (A) The man he killed on the way to Thebes was the king of Thebes. (B) The parents he fled in his "home" town weren't his biological parents; he was, in fact, born to the King of Thebes and Jocasta. So, yes, he's been sleeping with his mother and has killed his father.
When all this comes out, Jocasta kills herself and - finally, the relevant portion for the webcomic - Oedipus gouges his eyes out!
So, yes, this is how theatre history can make webcomics fun and exciting.